2359 Acute Liver Failure in the Setting of HSV-Induced Hemophagocytic Lymphohistiocytosis

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Acute liver failure caused by hemophagocytic lymphohistiocytosis in adults

BACKGROUND Hemophagocytic lymphohistiocytosis (HLH) is a rare condition that can be caused by a primary or acquired disorder of uncontrolled immune response. Liver injury is a common complication of HLH; however, HLH presenting as acute liver failure (ALF) has rarely been reported in adults. CASE SUMMARY A 34-year-old man was admitted to our hospital with nausea and fatigue persisting for 2 w...

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Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to c...

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Cyclosporine Induced Acute Kidney Injury in Hemophagocytic Lymphohistiocytosis

We describe a female patient in her 70s with haemophagocytic lymphohistiocytosis who developed an acute kidney injury secondary to cyclosporine use. Haemophagocytic lymphohistiocytosis (HLH) is a rare and severe immunologic disorder characterized by multiorgan system involvement, fever, rash, hepatosplenomegaly, cytopenias, and a range of neurologic manifestations. It is usually present in a pa...

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Diffuse Large B-Cell Lymphoma with Secondary Hemophagocytic Lymphohistiocytosis Presenting as Acute Liver Failure

Hemophagocytic lymphohistiocytosis (HLH) and newly diagnosed malignant infiltration of liver are rare presentations of acute liver failure associated with poor prognosis. We report a case of a patient with acute liver failure caused by malignant infiltration by diffuse large B-cell lymphoma and secondary HLH.

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Hemophagocytic lymphohistiocytosis complicated by multiorgan failure

RATIONALE We present a case of hemophagocytic lymphohistiocytosis (HLH) with severe pulmonary complication and acute respiratory distress syndrome (ARDS) hospitalized in our intensive care unit (ICU) in 2014; distinctive trait of this case has been the challenging diagnosis, with a bone marrow biopsy always negative, the severe pulmonary complication with ARDS and severe pulmonary hypertension,...

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ژورنال

عنوان ژورنال: American Journal of Gastroenterology

سال: 2019

ISSN: 0002-9270,1572-0241

DOI: 10.14309/01.ajg.0000598968.97660.72